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gentamicin sulfuric acid
【 traits 】 this product is colorless or almost colorless transparent liquid.
[pharmacological action] pharmacodynamics gentamicin aminoglycoside antibiotic, for a variety of gram-negative bacteria (e.g., escherichia coli, klebsiella, proteus, pseudomonas aeruginosa, pap bacillus, salmonella, etc.) and staphylococcus aureus (including producing beta lactamase strains) have antibacterial activity. most of streptococcus fluid (such as streptococcus, pneumococcus, streptococcus faecalis, etc.), anaerobic bacteria (bacteroides genus or clostridium), n/med tuberculosis bacili, rickettsia and fungal resistance to this product.
the pharmacokinetic intramuscular injection was absorbed quickly and completely after injection. at 0.5 ~ 1 hour the concentration of blood drug peak. the bioavailability of intramuscular injection is over 90%. the excretion of excretion is mainly through glomeruli, and the excretion is 40% ~ 80% of the dosage. after intramuscular injection of half-life, horse 1.8 ~ 3.3 hours, calf 2.2 ~ 2.7 hours, dogs and cats 0.5 ~ 1.5 hours, 1 hour cows, pigs, rabbits 1 ~ 2 hours, sheep, cattle, milk goats, buffaloes, 2.3 ~ 2.3 hours.
[drug interactions] 1. the combination of gentamycin and tetracycline and erythromycin may have antagonistic effects.
2. combined with cephalosporin, dextran, powerful diuretic drug (such as furthrice, etc.), erythromycin, etc., can enhance the ear toxicity of this product.
3. skeletal muscle relaxants (choline chloride, etc.) or drugs with this effect may enhance the neuromuscular retardation of this product.
【 indications 】 used in the treatment of sensitive gram negative and positive bacteria infection, septicaemia, urinary tract infections, respiratory infections, gastrointestinal infections, peritonitis, biliary infection, mastitis, and skin and soft tissue infection and infectious rhinitis etc.
[usage and dosage] intramuscular injection: at one time, every 1kg of weight, livestock 0.05 ~ 0.1ml; dog, cat 0.075 ~ 0.125 ml. two times a day, two to three days.
[adverse reactions] can result in vestibular function damage and can lead to reversible nephrotoxicity, which is related to the accumulation of renal cortex. i see an allergic reaction.
[note] 1. gentamycin can be combined with beta-lactamide to treat severe infection, but in vitro mixing is taboo.
2. combined with penicillin, this product has synergistic effect on streptococcus.
3. there is respiratory inhibition, unfavorable intravenous injection.
pig 40 days; 40 days for cattle and sheep.
[specification] 10ml:0.4g
packaging: 10ml x 10 / box
storage: kept in a cool dark place.
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