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【 main ingredient 】 the sulfuric acid ampucin.
【 traits 】 this product is tan powder.
【 pharmacology 】 (1) the pharmacodynamics for a variety of gram-negative bacteria (e.g., escherichia coli disease, false single spore bacillus, salmonella, klebsiella, proteus, pasteurella, swine dysentery treponema, bronchitis po generation bacterium) and staphylococcus and mycoplasma bactericidal activity. pyridoxal hydrochloride can strengthen the antibacterial activity of this product. apragaz toxin unique chemical structure can fight by multiple plasmids encoding passivation enzyme inactivated effect, thus gram-negative bacteria less resistant to its, many isolated from animal pathogenic escherichia coli and salmonella is sensitive to the illness. apycin and other aminoglycosides do not have cross-drug resistance caused by chromosomal mutations. it is mainly used to treat escherichia coli and other sensitive bacteria. it is also used to treat diarrhoea caused by bacillus calves and salmonella. e. coli, salmonella and mycoplasma infection are also effective.
(2) the internal medicine of pharmacokinetics is partially absorbed (especially newborn animals), the absorption amount is related to the dosage, and decreases with the increase of the animal's age. the drug is excreted in its original form through the kidneys. the half-life of calves, sheep, rabbits and chickens are 4.4, 1.5, 0.8 and 1.7 hours respectively.
[action mechanism] interferes with the synthesis of bacterial proteins. specifically, it interferes with the synthesis of prokaryotic proteins and inhibits harmful bacteria in animals and treats diseases caused by e. coli and salmonella. by inhibiting the proliferation of e. coli, improving the structure of the intestinal mucosa, promote the body's endocrine activities related to the growth (growth hormone adjustment, membrane island element) and t3 level of synergy and promote animal growth, improve feed utilization rate.
[drug interactions] 1. synergistic effect with penicillin or cephalosporin. 2. the antibacterial effect of this class of drugs in alkaline environment is enhanced, and the combination with alkaline drugs can enhance the effectiveness of antimicrobial activity, but the toxicity also increases accordingly. when ph is over 8.4, the antibacterial effect weakens. 3. ca2 , mg2 , na , nh4 , k and other cation can inhibit the antimicrobial activity of the drug. the concentration of these cationic ions should be noted in the culture medium. 4. combined with cephalosporin, dextran, diuretic and erythromycin, it can enhance the ear toxicity of these drugs. 5. skeletal muscle relaxants or drugs with this effect can enhance the neuromuscular retardation of the drug.
[indications] used to treat intestinal infection caused by gram-negative bacteria.
dosage: 125mg(1, 250, 000 units) per kilogram of weight, seven days of continuous drinking.
poultry: a solution of 250mg (250, 000 units) of ampulamycin is prepared to prevent continuous drinking of drinking water for three days for a course of treatment.
piglets prevention: as drug type feed premix during the suckling pig is recommended to use methods: 1. the piglets born 1-3 days, using soluble powder shechun soluble in water, every day at 12.5 mg/kg body weight (12500 units) for three consecutive days. 2. use the total period of 7 days -15 kg of suckling pig material and add 90 grams (0.9 billion units)/ton of feed. 3. if you would like to save cost: in addition to press 1 method used, can be used in whole period in the second stage suckling pig feed, feed add 90 grams (090 million units)/ton, poor environment, can be added to 165 grams (165 million units)/tons, from the age of 22 to 35 days of age stage use, also can be used to 42 days of age.
meat chicken: 5 grams (5 million units) of feed per 1000kg of feed is added to feed, and the use of full-length in 0-6 weeks will promote the growth of broiler chickens. premix: the concentration of 80-165 g (0.8-165 million units) per 100okg feed is added to pig feed for seven days.
[note] 1. drinking water must be prepared in the same day.
2. this product can be invalidated by rust, and the water system should be protected against rust. do not mix with trace element supplements.
[period] pig 21, chicken 7, egg production period is disabled.
[specification] 100g: apycin 50g(50 million units)
package: 100g/package x 10 pack/pail x 8 pail.
storage: shade, airtight, preserved in dry place.
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