haemophilus suis (hps) is the causative agent of swine fever and arthritis. in clinical and pathological studies, pigs are characterized by serous, fibrinous, inflammatory and inflammatory arthritis and high mortality. in addition, haemophilus pleuropneumoniae (hs) was added to actinobacillus pleuropneumoniae (ap) to induce contagious pleuropneumonia (pcpu) in pigs.
1. clinical symptoms
the occurrence of this disease first pig farm, the rapid onset of exposure to pathogens, within a few days after onset and high temperature reaction appeared, late tun, when forced motion or scream (pain), some pigs due to meningitis and muscle tremors, convulsions, paralysis. patient of limbs joint swelling, claudication, tremor, ataxia pain, visible mucous membrane cyanosis, side of death. when the bacteria through the skin wounds with blood and skin invasion or invasion, can cause local necrosis or inflammation of the skin, involving the ear, can cause ear necrosis.
2. changes in necropsy
a pig whose disease is characterized by a single or multiple serosal surface, including pleura, peritoneum, pericardium, meninges, and synovial membrane. serous and purulent fibrinous exudate occurs. arthritis is characterized by inflammation and edema of the joint surrounding the joint, enlarged cyst, increased synovial fluid, and a yellowish green purulent exudate. fibrinous purulent meningitis, subarachnoid cavity is due to see savings cerebrospinal fluid fibrino purulent exudate becomes turbid. other ocular lesions include congestion of the lung, liver, spleen and kidney, focal bleeding and swelling of lymph nodes. adhesions between the peritoneum and the abdominal cavity result in an increase in synovial fluid, including fibrin floc and concomitant articular cartilage lesions (showing rough surface of cartilage).
infectious haemophilus influenzae disease (inflammation and arthritis) that is resistant to penicillin, lin kenmei, and antibiotics. do not use it.
3. treatment measures
according to the study, the pathogen of this disease is sensitive to sulfa drugs. therefore, sulfa drugs such as sulfadiazine, sulfamethoxazole and sulfamethoxazole are often used as therapeutic agents. in 2003, it was reported that it was better to treat the disease with its own serum.
4. preventive measures
4.1. immunization of haemophilus parasuis multivalent oil emulsion inactivated vaccine, to sow colostrum by inoculation, the piglets less than 4 weeks of age to get protection, when the piglets were 4 weeks, then inoculated with the same vaccine to produce immunity (method and dosage according to the instructions). it is important to note that the hps serotypes are numerous, such as the type of serotypes contained in the vaccine being inoculated and the hps serotypes occurring, with excellent results or failure to cause immunity.
4.2. reduced the flow of piglets, advocate farrow, special feeding piglets trafficking in commercial farms, try to buy piglets from local area (due to the disease serotypes with local characteristics obviously), to prevent new serotype hps into this area.
4.3. strengthen management, maintain clean sanitation, good ventilation, cold case, try to reduce the intrusion of other respiratory pathogens, eliminate the production phase of the pig in different polyculture column, reduce pig flow, improve the disease resistance of pigs.
4.4. strengthen the pig nutrition management, in accordance with the health care method, add double coptis extract in 35kg in the feeder pig feed, enhance pig disease resistance, can very good prevention and control of the disease.
4.5. according to the pigs who have been infected with this disease, the introduction of antimicrobial agents in feed and drinking water to prevent the occurrence of hps has ended in failure. after suffering from this disease, oral antibiotics do not work.
4.6. this disease can be used as a kind of medicine, such as "chong xin", "yi", "fei", "chuan", "qi", "qi", "qi", "qi", "blood thirsty" and so on, or intramuscular injection or intravenous injection.
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