arthritis pig roughly caused by three factors, one is the porcine articular cartilage due to trauma or ligament damage, two is due to damp and cold stimulation, three is due to the occurrence of certain diseases caused by bacterial infection. haemophilus influenzae and streptococcus are important pathogens in arthritis caused by bacterial infection, and the differential diagnosis and treatment of arthritis are emphasized in the following.
arthritis due to infectious haemophilus influenzae disease
haemophilus suis (hps) is the causative agent of swine fever and arthritis. in clinical and pathological studies, pigs are characterized by serous, fibrinous, inflammatory and inflammatory arthritis and high mortality. in addition, haemophilus pleuropneumoniae (hs) was added to actinobacillus pleuropneumoniae (ap) to induce contagious pleuropneumonia (pcpu) in pigs.
1. clinical symptoms
the occurrence of this disease first pig farm, the rapid onset of exposure to pathogens, within a few days after onset and high temperature reaction appeared, late tun, when forced motion or scream (pain), some pigs due to meningitis and muscle tremors, convulsions, paralysis. patient of limbs joint swelling, claudication, tremor, ataxia pain, visible mucous membrane cyanosis, side of death. when the bacteria through the skin wounds with blood and skin invasion or invasion, can cause local necrosis or inflammation of the skin, involving the ear, can cause ear necrosis.
2. changes in necropsy
a pig whose disease is characterized by a single or multiple serosal surface, including pleura, peritoneum, pericardium, meninges, and synovial membrane. serous and purulent fibrinous exudate occurs. arthritis is characterized by inflammation and edema of the joint surrounding the joint, enlarged cyst, increased synovial fluid, and a yellowish green purulent exudate. fibrinous purulent meningitis, subarachnoid cavity is due to see savings cerebrospinal fluid fibrino purulent exudate becomes turbid. other ocular lesions include congestion of the lung, liver, spleen and kidney, focal bleeding and swelling of lymph nodes. adhesions between the peritoneum and the abdominal cavity result in an increase in synovial fluid, including fibrin floc and concomitant articular cartilage lesions (showing rough surface of cartilage).
infectious haemophilus influenzae disease (inflammation and arthritis). this bacterium is resistant to penicillin, lin kenmei, and must not be used frequently.
3. treatment measures
according to the research, the pathogen of sulfonamides, florfenicol, drug sensitive test for m magnitude, therefore, the new xin honggong chain, chuangxin no. 2, kang fu is bloodthirsty for drug treatment is often used. in 2009, it was reported that the treatment of this disease with its own serum had a better effect.
their serum preparation: homemade vaccine immunization program according to immune finishing pigs, a week after the injection of 10 ml; or with rehabilitation of diseased pigs, slaughter is sterile blood collection, separation of serum and inactivated virus cells, detoxification treatment in sterility test and animal test, after passing the 4 c or save spare from-20 deg.
method of use: one month old piglets per head with their serum 15 ml, a week after the injection of 25 ml of third injections when necessary, and adding long-acting sustained-release antibiotic in the serum, can obtain better curative effect. other larger piglets can increase the amount of serum properly.
4. preventive measures
4.1. immunization of haemophilus parasuis multivalent oil emulsion inactivated vaccine, to sow colostrum by inoculation, the piglets less than 4 weeks of age to get protection, when the piglets were 4 weeks, then inoculated with the same vaccine to produce immunity (method and dosage according to the instructions). it is important to note that the hps serotypes are numerous, such as the type of serotypes contained in the vaccine being inoculated and the hps serotypes occurring, with excellent results or failure to cause immunity.
4.2. reduced the flow of piglets, advocate farrow, special feeding piglets trafficking in commercial farms, try to buy piglets from local area (due to the disease serotypes with local characteristics obviously), to prevent new serotype hps into this area.
4.3. strengthen management, maintain clean sanitation, good ventilation, cold case, try to reduce the intrusion of other respiratory pathogens, eliminate the production phase of the pig in different polyculture column, reduce pig flow, improve the disease resistance of pigs.
4.4. strengthen the pig nutrition management, in accordance with the health care method, add double coptis extract in 35kg in the feeder pig feed, enhance pig disease resistance, can very good prevention and control of the disease.
4.5. of the bacteria to strong resistance, the new xin honggong chain, yan meters first, chuangxin no. 1, no. 2, drug sensitive morninglight. intramuscular injection or intravenous injection can be made with one of these drugs or combinations.
necropsy of diseased joint visible serofibrinous inflammation, joint capsule, synovial membrane surface hyperemia and rough opacity, and contains white cheese like lumps. some of the joints around the subcutaneous gelatinous edema, joint cartilage necrosis in severe cases, joints around the tissue has multiple purulent foci and necrosis.
3. diagnosis
according to the incidence of the disease, clinical symptoms, anatomical changes and laboratory examination, it can be diagnosed as arthritis caused by streptococcal infection.
4. treatment
promptly isolate the sick pigs and treat the sick and suspicious pigs. there are a lot of streptococcus sensitive drugs: penicillin, ceftiofur, cefradine, ampicillin, amoxicillin, florfenicol, sulfa, but because streptococcus has resistance, so the treatment dose should be sufficient, treatment should be complete, can be considered for use and combined wheel |
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